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Diffusible photoswitchable glutamate analogue presented in new paper


02.09.2015 10:58, Age: 3 yrs

Two-electrode voltage-clamp amplifier TEC-10.

Laprell et al. synthesized a diffusible photoswitchable glutamate analogue, which can be used to mimic synaptic input by one- or two-photon activation. The functionality of their photoswitch was validated by local drug application with one of npi electronic's PDES systems and oocyte two-electrode voltage clamp with npi's TurboTEC-10CX amplifier.

Laprell et al. (2015) Optical control of NMDA receptors with a diffusible photoswitch. Nat Commun (2015), doi:10.1038/ncomms9076