The ”optical multimeter” for probing brain circuits allows you:

  • optogenetic stimulation
  • and fluorescence measurement
  • via the same fiber

The applications are:

  • Localized measurement of physiological fluorescence signals (e.g. Ca2+ signals) from multiple sites in stimulation of physiological signals in disease model animals and drug testing freely behaving animals including primates 
  • Multi-color optogenetic stimulation
  • Near simultaneous optical measurement of cellular activity and optogenetic stimulation
  • Chronic monitoring of physiological signals in disease model animals and drug testing
  • Enhanced localized photodetection for deep-tissue multiphoton imaging
  • Combined fluorescence recording with fMRI imaging

Also available as stand-alone desktop version with 2 detectors and exchangeable filter cubes for dual fluorescence detection!!


Please contact us for more detailed information.


  • Dual-band excitation:
    450 - 490 nm (OGB1, GCamP, ChR2)
    550 - 590 nm (ArchT)
    Fluorescence recording in 500 - 540 nm band
  • short pulses at high power (optogenetics) on top of
  • constant low power illumination (fluorescence)
  • Ultrafast photodetector:
    hight robustness against high-dose irradiation detecting fluorescence signal immediately after optogenetic stimulation with high sensitivity
  • can also be used as supplemental photodetector channel for multiphoton microscopy
  • compatible with multi-mode SMA fibers incl. non magnetic fibers for fMRI

Technical Data

Available central wavelengths (LED):
450 nm, 470 nm, 570 nm, 617 nm, 625 nm

Excitation band:
450 - 490 nm (blue)
540 - 590 nm (orange)

Max. light power at 200 µm fiber tip:
110 mW/mm2 (blue)
65 mW/mm2 (orange)

Fiber interface:

Fluorescence detection band:
500 - 540 nm (green)

Fluorescence signal output filter:
200 Hz low-pass (add-on block)

Fluorescence signal output range:
0 ~ -5 V (negative polarity)

Requires 2 module slots of EPMS chassis

Power consumption: